ABSTRACT
Statement of Problems: Candida species are the most common fungal pathogen in human's body. Therefore an accurate and immediate treatment seems to be necessary. Nowadays, alternative treatments, such as probiotics, are considered because of the adverse side effects of chemical medications. Probiotics are alive organisms which can be used for medical purposes and are added to different kinds of diary such as yoghurt. Lactobacill Acidophilus [LA] was detected form human's recourses many years ago and nowadays can be found in special kinds of milk, yoghurt, juice and food complementories
Purpose: In this study we are to compare the effect of conventional pasteurized and lactobacillus acidophilus- fortified pasteurized yoghurt on Candida Albicans in vitro
Materials and Method: Candida Albicans was isolated from 30 oral candidasis patients, cultured and prepared as standard suspension. Probiotic powder of LA in MRS Media after 24hrs led to 5x10[9] lactobacillus. LAfortified yoghurt was prepared via adding lactobacills into 250 ml of pasteurized boiled milk after 8hrs in 37[degree]c. We prepared 3 tubes and added standard suspension of Candida in each of them. Adding sterile yoghourt, conventional pasteurized yoghurt and LAfortified yoghurt to the tubes respectively, we put them in 35[degree]c incubator for 48 hrs. We added the content of each tube in Sabouraud agar media and incubated in 25[degree]c for 72 hrs and then counted the colonies
Results: There was a significant difference between the mean of colonies in each group during 5 days [p = 0, df = 4] and also on each day [p = 0, df = 2]
Conclusion: L.A. can inhibit colonization of Candida in vitro. In this study the most of Candida colonies were in the sterile yoghurt and the least of them were in LA fortified yoghurt
ABSTRACT
Statement of Problem: The central nervous system and oral cavity have a close anatomical location. Recognition of the orofacial manifestations of neurological diseases is in direct relation with the responsibilities of a dentist
Purpose: The objective of this study was to familiarize dentists and even physicians with orofacial manifestations of related neurological diseases
Materials and Method: This cross- sectional study was performed on 1284 patients with known cases of neurological diseases referred from all over the Southern Provinces of Iran to Oral Medicine Department of Shiraz Dental School from 1997 to 2010. Orofacial manifestations of 34 different types of neurological diseases were classified in four main groups of cranial nerve disorders, main neurological disorders, neoplastic and tumoral neurological lesions and congenital anomalies of neurological disease. These groups were evaluated with respect to age, sex, signs and symptoms, clinical appearance and location of the lesions. Data were analyzed by using SPSS software version 15, by using relative frequency and frequency quotients
Results: Orofacial manifestations were shown in 532 patients of the first group [41.48%], 386 patients of the second group [30.11%], 243 patients of the third group [18.93%] and 123 patients of the fourth group [9.48%], respectively
Conclusion: According to the results of this 14 years study, cranial nerve disorders showed most of oral signs and symptoms followed by main neurological disorders, neoplastic and tumoral lesions, and congenital anomalies of neurological diseases respectively. So, dentists should be familiar with these manifestations to have a better recognition, diagnosis and correct decision upon treating these manifestations in such patients
ABSTRACT
Statement of Problem: Oral lichen planus [OLP] is a chronic inflammatory disorder which can specially be painful in atrophic, erosive and ulcerative forms. In this area, different treatment plans with different results have been evaluated
Purpose: The aim of this article is to compare the effect of aloe vera gel and local triamcinolone in treatment of oral lichen planus lesions
Materials and Method: In this double blind research, 50 patients [13 males and 37 females] having oral lichen planus lesions were selected and randomly divided into two groups. The first group received 70% aloe vera gel and the second group, 0.1% local triamcinolone. Both groups used the drug locally 3 times a day for 8 weeks. All the patients were under follow up every 2 weeks. Clinical evaluation and pain reduction was evaluated by Thongprasom and VAS methods in both groups. Data were evaluated by repeated measure technique
Results: 20 patients of the triamcinolone group showed good response to treatment and 3 patients had complete remission during the treatment period. In aloe vera group, 9 patients had good response and no one showed complete remission [p <0.001]. No significant lesion was seen in both groups during the treatment period
Conclusion: Application of aloe vera gel is suggested in treatment of erosive and atrophic lichen planus lesions in comparison with steroids. However, according to the results of this study, the use of steroid instead of aloe vera in treating ulcerative lichen planus lesions is a better and more appropriate choice
ABSTRACT
Leukoplakia, is considered as the most common precancerous oral lesion. Numerous researches have shown that the effect of various risk factors in malignancy of leukoplakia differs in different societies. Being so, this study was desighned to evaluate the probability rate of malignant transformation of oral leukoplakic lesions in relation to risk factors of age, sex, smoking habit of patients, clinical appearance and site of the oral lesions in Shiraz from 1368 to 1388. This retrospective analytical-descriptive research was performed by collecting all leukoplakia from the Shiraz Nemazi and Khalili Hospitals as well as Oral Medicine and Oral Pathology Departments of Shiraz Dental School from 1368 to 1388 were selected according to their files. Patients with malignant transformation considered as the target group and those without such transformation named control group. Risk factors such as age, sex, smoking habit, clinical appearance and site of the lesions, as independent factors were evaluated in relation to their effect in malignant transformation of the oral leukoplakia through recording of necessary data via filling of special questionnaires. Chance rate in both groups was also evaluated. Data were analyzed by Excell, SPSS and Epi statistical software. Malignant transformation rate of oral leukoplakia was 40.8%. This rate showed increase with age increase specially after, forty years. The malignancy rate in females after the age of forty was higher than males. Although smoking will increase the chance of oral leukoplakia, most malignant transformations, were seen in non-smokers. Tongue was the most site and lips were the least common site for malignant transformation and white and red lesions [erythroplakic lesions] have the highest rate of malignant transformation in both sexes. Data, showed that factors such as age, sex, smoking habit, clinical appearance and site of oral lesions were in direct relation to malignant transformation of oral lesions of leukoplakia
ABSTRACT
Statement of problem: Awareness of clinical dental students' points of view about the educational situation of different departments will help faculty members and those in charge of educational affairs to improve the students' qualitative as well as quantitative scientific skills. Being so, to achieve such a goal, it seems necessary to conduct a research on evaluation of educational condition of different dental departments from students' points of view
Purpose: The aim of this study was to evaluate the weak and strong points of different departments of Shiraz Dental School as determined by dental students' points of view in order to present new methods to improve future educational policies of dental departments
Materials and Method: In this cross-sectional study, a questionnaire made of seventeen standard questions was used. After confirmation of the validity of the questions, the questionnaires were distributed among 43 fifth and sixth year students of Shiraz Dental School. After completion of the questionnaires, the data were analyzed by Kruskall- Wallis and Mann- Whitney tests, using SPSS software
Results: Based on the results of this study, although there was a low rate of fluctuation in the students' rate of satisfaction from educational situation of different departments, the highest satisfaction rate was belonged to pedodontics and periodontics departments respectively, and the least satisfaction rate belonged to oral surgery department
Conclusion: In spite of the difference in answers given to similar questions such as scientific capability of faculty members, equipment of departments and behavior of personnel and faculty members to students, generally speaking, the rate of students' satisfaction from different departments was almost similar to each other and had a low fluctuation rate [ p > 0.05]
ABSTRACT
Papillon- Lefevre Syndrome [PLS] is a rare, autosomal recessive disease with no known etiological factor, which reveals loss of function mutations affecting both the alleles of the cathepsin- C gene. The disease is characterized by palmo-plantar keratoderma and early juvenile periodontitis affecting both primary and permanent teeth. Due to the severe alveolar bone loss both in deciduous as well as permanent dentitions, teeth are exfoliated within two or three years after eruptions. By the age of 15 or 16, patients are usually edentulous except for the third molars. These teeth are also lost a few yeas after they erupt. No treatment has been shown to be effective for keeping teeth. Prognosis for prevention of teeth loss is hopeless. Available treatment plans such as stabilization of the alveolar bone height improve the prognosis for a lifetime of complete denture use. In this article, a- 12- year old girl living in Bandar Abbas who has been referred to Oral Medicine Department of Shiraz Dental School for further evaluation, diagnosis and proper treatment plan is reported
ABSTRACT
Pain is one of the most commonly experienced symptoms in medicine and, as such, is a major concern to the physician. The word pain has been used by almost every one and has been described by a variety of terms and according to personal past experiences and memories of it. Pain is not only considered as a specific sensation associated with actual or potential tissue damage but also depends on cultural background, cognitive, motivational and affective factors, personality, attention and so on. Being so, with the full knowledge that any definition for pain is arbitrary and open to question, one may define pain with its multidimensional nature as an unpleasant sensation created by a noxious stimulus which acts as a protective mechanism. Pain not only includes a sensory discriminative component but also involves the accompanying reaction elicited by the stimulus. So, the study, diagnosis, and treatment of pain requires the recognition of all those factors related to the pain experience. Accordingly, familiarity with stimulation and measurement techniques and theories of pain and their related mechanisms, will be a necessity to apply pain control procedures. The purpose of this article is a relatively comprehensive review in pain continuum and its specifications based on biologic principles with the emphasis on relationship of pain mechanisms with oro-facial areas